iSGTW - International Science Grid This Week
iSGTW - International Science Grid This Week
Null

Home > iSGTW 23 April 2008 > iSGTW Image of the week: The micro-world of muscle cells

 

Image of the week - The micro-world of muscle cells


These four visualizations show four sections of a muscle cell, each comprising several saromeres. Different colours indicate different organelles, including the myofibrillar system, sarcoplasmic reticulum, mitochondria and t-tubules. The cell envelope is rendered transparently.
Image courtesy of GeomCell

Enter the micro-world of your muscle cells, and you’ll find the entire length of a muscle “fiber” is actually a single cell.

Called “skeletal muscle cells,” these giants are comprised of a number of repeating units, called sarcomeres, which contain cellular organelles such as myofibrils, mitochondria, t-tubules and sarcoplasmic reticulum.

These organelles, even if of the same type, vary widely in their size, shape and location within the cell. Moreover, they often display complex spatial relationships.

To understand the complexity of a muscle cell, realistic computer models are instrumental and may serve as a virtual cell for experiments, allowing scientists to assess the validity of stereological and morphological techniques.

Modeling your muscle

A good muscle cell model must maintain the typical morphological characteristics of organelles—such as topology, shape, volume and surface area—as well as their spatial organization within the scene.

The GeomCell modeling system, created by UMFG SAS and ported to the EGEE grid by II SAS, provides the user with flexible tools to build organelles with arbitrary topology within the muscle cell infrastructure. This allows users to create realistic 3D scenes of the micro-world of muscle cells. Such visualizations provide some means for ascertaining the fidelity of the model or the plausibility of the cell structure.

 

Tags:



Null
 iSGTW 22 December 2010

Feature – Army of Women allies with CaBIG for online longitudinal studies

Special Announcement - iSGTW on Holiday

Video of the Week - Learn about LiDAR

 Announcements

NeHC launches social media

PRACE announces third Tier-0 machine

iRODS 2011 User Group Meeting

Jobs in distributed computing

 Subscribe

Enter your email address to subscribe to iSGTW.

Unsubscribe

 iSGTW Blog Watch

Keep up with the grid’s blogosphere

 Mark your calendar

December 2010

13-18, AGU Fall Meeting

14-16, UCC 2010

17, ICETI 2011 and ICSIT 2011

24, Abstract Submission deadline, EGI User Forum

 

January 2011

11, HPCS 2011 Submission Deadline

11, SPCloud 2011

22, ALENEX11

30 Jan – 3 Feb, ESCC/Internet2

 

February 2011

1 - 4, GlobusWorld '11

2, Lift 11

15 - 16, Cloudscape III


More calendar items . . .

 

FooterINFSOMEuropean CommissionDepartment of EnergyNational¬†Science¬†Foundation RSSHeadlines | Site Map